Minimally invasive surgery less effective than open surgery for cervical cancer

Alicia Farmer
November 3, 2018

In an analysis of data from throughout the United States, they noted that survival for women undergoing radical hysterectomy for cervical cancer remained relatively constant until about 2006. Half of the women had minimally invasive surgery.

"This result is very surprising, since randomized trials have demonstrated the safety of minimally invasive surgery for uterine, gastric and colorectal cancers", Melamed said. "I chose minimally invasive thinking it was the best, latest and greatest and best thing to do", Andersson said.

When a woman is diagnosed with cervical cancer, she often gets her uterus and cervix removed, an operation known as a radical hysterectomy.

However, two new studies could change all that. That suggests that cervical cancer cells may be released more readily during a procedure.

Women who had minimally invasive hysterectomies, including those using robots such as the Da Vinci device, were more likely to have their cancer come back and kill them than women who had more invasive "open" surgery, the researchers found.

The results were startling and strong enough to change practice in at least one major cancer center, MD Anderson in Texas.

The findings did not make sense to the researchers, who believed that women who got less invasive surgery should do better, not worse, than those who got more old-fashioned, invasive operations. Compared with open surgery, minimally invasive surgery correlated with a lower rate of disease-free survival (three-year rate, 91.2 versus 97.1 percent; hazard ratio for disease recurrence or death from cervical cancer, 3.74; 95 percent CI, 1.63 to 8.58) and with a lower rate of overall survival (three-year rate, 93.8 versus 99.0 percent; hazard ratio, 6.00; 95 percent CI, 1.77 to 20.30). It usually leads to less bleeding, fewer infections and fewer complications.

For the last decade, minimally invasive surgeries have been gynecologists' preferred choice for treating early-stage cervical cancer.

"Given these two studies, we believe that we can no longer recommend minimally invasive radical hysterectomies for our patients with early stage cervical cancer", Rauh-Hain said.

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"Do these studies signal the death knell for minimally invasive radical hysterectomy in cervical cancer patients?"

But after 2006, survival rates began to fall by about 0.8 percent per year, the team reported.

The studies were published online Wednesday in the New England Journal of Medicine.

One study team looked at almost 2,500 women with stage 1 cervical cancer in 2010-2013. You will have inputs regarding company profiling of Minimally Invasive Medical Robotics market leading manufacturers plus their contact information, sales, market share, product picture and specification.

These women were also less likely to be alive 4 1/2 years following the surgery.

A new Research Study, Global Minimally Invasive Surgery Market Professional Survey Report 2018, presented by QY Market Insights is a complete study made by implementing a wonderful research procedure to assemble key data of this worldwide market. "An alternative explanation is that USA surgeons could have been less experienced with the minimally invasive procedure than with open surgery during the study period". In the study, there was no evidence that women who were getting the minimally invasive surgery had more residual tumors than women getting the open surgery.

Ramirez says surgeons at MD Anderson "decided to stop offering the minimally invasive radical hysterectomy and completely convert to the open approach". So Andersson is being treated with radiation and chemotherapy. "It included a large number of centers throughout the world, and all centers were required to demonstrate proficiency in minimally invasive surgery". This report offers examination and increment pace of the market in these districts covering North America, Europe, China, Japan, India, Southeast Asia, Other regions (Central & South America, Middle East & Africa).

"And it has been thought that perhaps the carbon dioxide gas may have a role in causing a higher risk of cell implantation within the abdominal cavity", Ramirez told NBC News.

Surgical skill may also be a factor, said Melamed. Mainly, the complete scrutiny of the companies that are offered in the marketing and production of Cardiothoracic Minimally Invasive Surgical Instruments based on previous and futuristic market condition and market break down on the Cardiothoracic Minimally Invasive Surgical Instruments market segments that include Key Players, Types, Applications, Regions Moreover, a detailed study of Cardiothoracic Minimally Invasive Surgical Instruments market dynamic facts that provides a comprehensive estimation of the driving and growth factors, Cardiothoracic Minimally Invasive Surgical Instruments developing countries, various company norms, obstacles, and opportunities pertinent in the Cardiothoracic Minimally Invasive Surgical Instruments market report.

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